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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DNM1L All Species: 18.79
Human Site: S533 Identified Species: 29.52
UniProt: O00429 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00429 NP_005681.2 736 81877 S533 S A V S R D K S S K V P S A L
Chimpanzee Pan troglodytes XP_520720 896 98575 S693 S A V S R D K S S K V P S A L
Rhesus Macaque Macaca mulatta XP_001086126 725 80517 R522 Q R R N R L A R E L P S A V S
Dog Lupus familis XP_864886 736 81869 S533 S A V S R D K S Y K V P S A L
Cat Felis silvestris
Mouse Mus musculus Q8K1M6 742 82640 S539 S A G S R D K S S K V P S A L
Rat Rattus norvegicus O35303 755 83890 S546 S A V S R D K S S K V P S A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001073190 696 77727 D500 Y I N T K H P D F A D A C G L
Frog Xenopus laevis NP_001080183 698 77807 N510 D A C G L I N N N I E E Q R R
Zebra Danio Brachydanio rerio Q7SXN5 691 77244 I493 V A I E L A Y I N T K H P D F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P27619 877 97791 S532 L G I M K G G S R P Y W F V L
Honey Bee Apis mellifera XP_394947 721 81070 D518 L L K N S N V D H I K H N R K
Nematode Worm Caenorhab. elegans P39055 830 93389 G536 S N V S F V R G S K D N W F V
Sea Urchin Strong. purpuratus XP_802061 717 80361 N515 V E Q N D R E N S R K S T R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LFT2 780 86625 V544 V A R P R D T V E P E R T A S
Baker's Yeast Sacchar. cerevisiae P54861 757 84953 L559 Q E L L K S K L S Q Q E N G Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.5 98.5 99.1 N.A. 97.8 96.4 N.A. N.A. 89.8 87 86 N.A. 33.9 66.8 35.6 68.7
Protein Similarity: 100 79.9 98.5 99.5 N.A. 98.3 97.2 N.A. N.A. 91.8 90.9 90.3 N.A. 52.2 79.7 53.9 82.2
P-Site Identity: 100 100 6.6 93.3 N.A. 93.3 100 N.A. N.A. 6.6 6.6 6.6 N.A. 13.3 0 33.3 13.3
P-Site Similarity: 100 100 20 93.3 N.A. 93.3 100 N.A. N.A. 20 20 20 N.A. 26.6 20 46.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. 42.4 45.5 N.A.
Protein Similarity: N.A. N.A. N.A. 59.4 65.2 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 54 0 0 0 7 7 0 0 7 0 7 7 40 0 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 7 0 0 0 7 40 0 14 0 0 14 0 0 7 0 % D
% Glu: 0 14 0 7 0 0 7 0 14 0 14 14 0 0 0 % E
% Phe: 0 0 0 0 7 0 0 0 7 0 0 0 7 7 7 % F
% Gly: 0 7 7 7 0 7 7 7 0 0 0 0 0 14 0 % G
% His: 0 0 0 0 0 7 0 0 7 0 0 14 0 0 0 % H
% Ile: 0 7 14 0 0 7 0 7 0 14 0 0 0 0 0 % I
% Lys: 0 0 7 0 20 0 40 0 0 40 20 0 0 0 7 % K
% Leu: 14 7 7 7 14 7 0 7 0 7 0 0 0 0 54 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 7 20 0 7 7 14 14 0 0 7 14 0 0 % N
% Pro: 0 0 0 7 0 0 7 0 0 14 7 34 7 0 0 % P
% Gln: 14 0 7 0 0 0 0 0 0 7 7 0 7 0 7 % Q
% Arg: 0 7 14 0 47 7 7 7 7 7 0 7 0 20 7 % R
% Ser: 40 0 0 40 7 7 0 40 47 0 0 14 34 0 14 % S
% Thr: 0 0 0 7 0 0 7 0 0 7 0 0 14 0 0 % T
% Val: 20 0 34 0 0 7 7 7 0 0 34 0 0 14 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % W
% Tyr: 7 0 0 0 0 0 7 0 7 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _